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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018



Zone de texte éditable et éditée et rééditée

Metabolites profiling

Metabolics profiling (Metabolite profiling) is the analysis of all metabolites in a pathway or those of a particular class. This may be achieved by mass spectrometry or NMR. Methods of separation of metabolites used are mainly based on liquid chromatography (LC), gas (GC) or even on plate (TLC). With these methods, it is possible to monitor the evolution of metabolites in a pathway or in interconnected pathways.

Analyzes :

  • Culture supernatant analysis by NMR 500MHz
  • Quantitative metabolomics analysis by IC-MS/MS
  • Culture supernatant analysis by HR-RMN 800MHz
  • Suspects screening
  • Untargeted analyis by LC-HRMS


profilage metabo


These analyzes can also been completed by structural analyzes carried out by NMR and/or mass spectrometry for the identification of unknown compounds (natural products, contaminants, metabolites produced in vivo or in vitro in animals or plants, etc.).

  • Structural analysis by MS
  • Structural analysis by NMR

Research and Development in Metabolites profiling:

  • Development of LC-HRMS methods using stable isotopes for the characterization of fungal secondary metabolites
  • Development of LC-HRMS methods for the analysis of particular class of metabolites (adducts, aldehydes)
  • Development of NMR methods for the analysis of new classes of metabolites