Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free: https://www.ghostery.com/fr/products/

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site: http://www.youronlinechoices.com/fr/controler-ses-cookies/, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Realytics
Google Analytics
Spoteffects
Optimizely

Targeted advertising cookies

DoubleClick
Mediarithmics

The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at cil-dpo@inra.fr or by post at:

INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu INRA logo envt small Logo INP-EI Purpan Logo UPS-Tlse3

Home page

Zone de texte éditable et éditée et rééditée

The Team

The COMICS Team

L'équipe E12 COMICS

Laurence HUC

photo Laurence 2

ORCID ID : 0000-0002-0336-7559
ResearcherID: J-1888-2014
researchgate

Chargée de Recherche (Senior Researcher)
Magistère ENS-Lyon, PhD, HDR
Tel : +33 582 06 63 20
Fax : +33 561 28 53 10
Laurence.Huc@inrae.fr

  • Laurence completed her thesis in molecular and cellular toxicology in the INSERM U620 laboratory, under the direction of Dominique Lagadic-Gossmann, on the regulation of intracellular pH during apoptosis induced by benzo [a] pyrene, a polycyclic aromatic hydrocarbon , in liver cells. She then worked as a postdoctoral fellow at Oxford University on intracellular pH in heart cells, and then at Imperial College London in the Experimental Medicine and Toxicology laboratory on apoptosis induced by anticancer agents. In October 2008, she was recruited to develop molecular and cellular studies in food toxicology. Since then, she has worked on the mitochondrial stress induced by bisphenol A, on the study of cell death and detoxication of 4-hydroxynonenal in normal and pre-cancerous colonic cells according to a process of Darwinian carcinogenesis. Since the creation of COMICS team, she works on the metabolic reprogramming upon food exposure by polycyclic aromatic hydrocarbones and dioxins, related to chronic diseases, such as cancer (INCa METAhCOL project). She coordinates a project for alternative in vivo models with zebrafish (funding from Canceropole Grand Sud Ouest (Toxinzebra)). She carries out studies related to mitochondria-targeted fungicides, like succinate deshydrogenase inhibitors (SDHi). In order to set up an activity of conceptual toxicology, she is a master 2 student in logic, philosophy of sciences and philosophy of knowledge (LOPHISC) at Sorbonne-University. She is a member of the Institute for Philosophy in Biology and Medicine (PhilInBioMed) coordinated at the University of Bordeaux. She is concerned by citizen sciences and the co-construction of knowledge. She a member of the platform  Génotoul Sociétal, pluridisciplinary group dedicated to scientific public debates and bioethics. She takes part in the discussion about the dialog between academics and participatory sciences in collaboration with ALLISS and is involved in the task force of the group dealing with chronic risks and related diseases in the context of open science.

Elisa BOUTET-ROBINET

photo Elisa 2

ORCID ID : 0000-0002-5223-4568
ResearcherID:  Q-1342-2015
researchgate

Professor in Toxicology, Faculty of Pharmacy, Toulouse
PharmD, PhD, HDR,
Tel : +33 582 06 63 44
Fax : +33 561 28 53 10
elisa.boutet@univ-tlse3.fr

  • Elisa, a pharmacist by training, prepared a thesis in pharmaco-toxicology of G-protein coupled receptors, within Pierre Fabre Laboratories, specializing in cell signaling. After a post-doctorate at Inserm (Laboratory of Biology and Digestive Pathology) and a ATER position, Elisa was recruited as a lecturer in Toxicology in 2005 at Paul Sabatier University (Toulouse III) Faculty of Pharmacy. She first worked in epidemiology and public health, in close collaboration with the Institute of Public Health, Epidemiology and Development (ISPED) of Bordeaux in the context of occupational exposure to pesticides. In order to develop molecular epidemiology projects, Elisa joined the team of Bernard Salles at CNRS and ToxAlim in 2011, where she first studied pesticides and their ability to generate DNA damage in farmers' cohorts  by coordinating two INCA Cancer Environment projects. She has diversified her research by studying the genotoxicity of pesticides and other contaminants (e.g. titanium dioxide in nanoparticulate form) on relevant experimental models in the context of dietary exposure.

Thierry Gauthier

thierry IMG_2322-1petite

ORCID ID : 0000-0003-0207-0515
Research Engineer (IR1)
Engineer in Biotechnology and PhD in cell physiology
Tel : +33 582 06 63 81
Fax : +33 561 28 53 10
Thierry.Gauthier@inrae.fr

  • Dr Thierry Gauthier received in 1986 his Biochemical Engineer certificate (National Institute of Applied Sciences of Toulouse, France) and in 1989 his PhD degree (University Paul Sabatier, Toulouse, France). After obtaining his certificates, he worked for 2 years as Biochemist in a start-up company specialised in the development of recombinant proteins displaying properties preventing graft rejection. Since then, he joined INRA in 1993 and was responsible for 15 years of the Industrial Partnership and the Intellectual property within the Animal Health Division. In that view, he followed an additional training regarding contracts and intellectual property (IRPI, Paris). Since 2009, he moved to Toxalim Unit where he set up a Cell Imaging Platform equipped with a flow cytometer (MACSQuant Miltenyi) and a confocal microscope (SP8, Leica). Besides, he was involved in research projects dealing with toxic effects of mycotoxins (deoxynivalenol, trypacidine, patuline, Versicolorine A) and 4-hydroxynonenal. He recently joined the team Comics (April 2018) where he is involved in the study of cell response driving cell death to food contaminants such as pesticides.

Saleha HASHIM

Saleha

Technician (Faculty of Pharmacy)
saleha.hashim@inrae.fr

  • Saleha was recruited in the Toxicology Department at the Faculty of Pharmacy of Toulouse (Paul Sabatier University) in 2008. She worked from 2008 to 2010 at l'IPBS in Bernard Salles team, and from 2010 to 2020 in GS Team (Gladys Mirey) at ToxAlim. She joined the Comics team in September 2020. At the faculty, Saleha takes care of the preparation of practical work for 3rd year students. In the team, Saleha will carry out essential logistical missions (orders, laboratory management). Saleha is involved in the experiments of the team's scientific projects (techniques: cell biology, biochemistry and molecular biology) and in missions of collective interest (cell quality, metrology, autoclave control, liquid nitrogen handling).

Augustin LE NAOUR

Photo Augustin Le Naour_2

ORCID ID : 0000-0003-1790-4543

Maître de Conférences en Toxicologie, Faculté de Pharmacie
PharmD, PhD
augustin.le-naour@univ-tlse3.fr

  • Augustin accomplished his initial training as a pharmacist at Bordeaux Segalen University. He then completed his thesis on the effect of the tumor microenvironment in ovarian cancer in the INSERM U1037 laboratory in Toulouse, under the supervision of Pr. Bettina Couderc. He has notably worked on the effect of mesenchymal stromal cells and macrophages in resistance to chemotherapy. He then completed 2 years of ATER (temporal researcher and lecture) at Clermont Auvergne University in the human nutrition unit of UMR INRA-UCA 1019 where he studied the effect of nutrition and physical activity on tumor development of breast cancer. After a post-doctorate in UMR152 UPS-IRD, Augustin was recruited in 2020 as associate professor in Toxicology-Semiology at the Faculty of Pharmacy at Paul Sabatier University in Toulouse and he joined the COMICS team at ToxAlim.

Liana ARNAUD

liana

PhD student, janv 2018-2020 (Project METAhCol)
Liana.Arnaud@inrae.fr

  • After obtaining a bachelor’s degree of Cell Biology and Animal Physiology at the University Paul Sabatier of Toulouse, Liana continued her studies by a BioSanté master's degree specialized in "Digestive Health and Nutrition" at University Paul Sabatier of Toulouse. Liana is PhD student in the team and studies the impact of food contaminants on metabolic reprogramming.

Carolina Duarte-Hospital

carolinaIMG_2324-1petite

PhD student, oct 2018-2020 (Project SDHi), co-mentorship with Sylvie Bortoli and Xavier Coumoul, Paris Descartes University
carolina.duarte_hospital@etu.parisdescartes.fr

  • After graduating as an Agricultural Engineer at the Universidad Nacional de Asuncion (2013) in Paraguay, followed by a first job at Cargill company, Carolina has decided to continue her studies with the Master Nutrition and Food Science (mention «Health risk analyses related to food») at AgroParisTech (Master internship in Toxalim, with Thierry Gauthier). Carolina is currently PhD student with a joint doctoral program between Toxalim and INSERM UMR-S 1124 (Paris), she studies the impact of SDHi fungicides (succinate dehydrogenase inhibitors) on metabolic reprogramming and epigenetic reprogramming.

Marie KERHOAS

Marie_Kerhoas_2

PhD student, oct 2020-2023
Marie.kerhoas@inrae.fr

  • After obtaining a degree in Pharmacy and a Master's degree in Biohealth "Human Toxicology, Risk Assessment and Vigilance" at the University of Paris Descartes (Master's internship at ToxAlim with Thierry Gauthier and Elisa Boutet-Robinet), Marie pursues her training by completing a university thesis. She is currently PhD student in the team and studies the mechanisms of toxicity of succinate dehydrogenase inhibitor fungicides and their carcinogenic potential.

See also